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Born in Washington, D.C., to a African-American mother and a Puerto Rican father, Amythsx spent half of her childhood in Maryland influenced by reggae, salsa, and gogo music. She attended the Maryland Institute College of Art in Baltimore City to pursue a bachelors in fine art. In Baltimore City she became involved in the underground music scene while working as a promoter for Abdu Ali's music event Kahlon. While working as a promoter she was constantly surrounded by local performers which eventually inspired her to DJ. Amythsx started to DJ in February 2016 with an array of genres such as jazz, punk, EDM, pop, hip hop, r&b, reggae, and reggaeton. Her mission as a DJ is to intertwine every genre and also educate listeners by playing the original tracks that are sampled in pop culture.